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Accession: PRJNA286202 ID: 286202

Mus musculus (house mouse)

Transcriptome-wide mapping of RNA:protein interactions of seven SR proteins and NXF1 in P19 cells by iCLIP

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This project is a component of the SR protein family in P19 cells
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1 additional project is a component of the SR protein family in P19 cells.
47588 additional projects are related by organism.
We used GFP-tagged SR proteins expressed at endogenous levels and iCLIP to identify and compare endogenous RNA targets of individual SR proteins, map the preferential sites of binding, compare binding pattern and binding motifs between family members and to NXF1 and quantify binding of SR proteins and NXF1 to spliced versus unspliced RNAs to study the role of SR proteins in mRNA export via NXF1. More...
AccessionPRJNA286202; GEO: GSE69689
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsMüller-McNicoll M et al., "SR proteins are NXF1 adaptors that link alternative RNA processing to mRNA export.", Genes Dev, 2016 Mar 1;30(5):553-66
SubmissionRegistration date: 9-Jun-2015
RNA Regulation Group, Institute for Cell Biology and Neuroscience, Goethe University Frankfurt
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments35
Publications
PubMed1
PMC1
Other datasets
BioSample35
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes152
SRA Data Details
ParameterValue
Data volume, Gbases64
Data volume, Mbytes43630

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