See
Genome Information for Homo sapiens
To compare the genome wide binding profiles of SOX2 in hESCs and hNPCs, we carried out SOX2 ChIP-seq in the two cell types and dissected the the cell type and stage dependent regulatory groups of SOX2, thus providing important information for the mechanism underlying SOX2's dynamic functions in hESCs and hNPCs.
Overall design: Comparative analysis of SOX2 genome-wide occupancy in hESCs and hNPCs
| Accession | PRJNA285791; GEO: GSE69479 |
| Data Type | Epigenomics |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Zhou C et al., "Comprehensive profiling reveals mechanisms of SOX2-mediated cell fate specification in human ESCs and NPCs.", Cell Res, 2016 Feb;26(2):171-89 |
| Submission | Registration date: 2-Jun-2015
Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 6 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 6 |
| GEO DataSets | 1 |