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Accession: PRJNA285744 ID: 285744

Mus musculus (house mouse)

Expression data from Lineage-c-Kit+Sca-1+ (LSK) and megakaryocyte/erythroid progenitor (MEP) cells isolated from JAK2V617F/Ezh2Δ/Δ mice post JQ1 treatment

See Genome Information for Mus musculus
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This project is a component of the Understanding the role of EZH2 insufficiency in the pathogenesis of PMF
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1 additional project is a component of the Understanding the role of EZH2 insufficiency in the pathogenesis of PMF.
47588 additional projects are related by organism.
Loss-of-function mutations in EZH2 are associated with worse outcomes in patients with primary myelofibrosis (PMF). More...
AccessionPRJNA285744; GEO: GSE69499
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsSashida G et al., "The loss of Ezh2 drives the pathogenesis of myelofibrosis and sensitizes tumor-initiating cells to bromodomain inhibition.", J Exp Med, 2016 Jul 25;213(8):1459-77
SubmissionRegistration date: 3-Jun-2015
Sashida Lab, IRCMS, Kumamoto University
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots222724
Data volume, Processed Mbytes5
Data volume, Supplementary Mbytes13

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