Sign in to NCBI

Display Settings:

Format

Send to:

Choose Destination
Accession: PRJNA285668 ID: 285668

Homo sapiens (human)

The phosphorylated prodrug FTY720 is a histone deacetylase Q15 inhibitor that reactivates ERα expression and enhances hormonal therapy for breast cancer

See Genome Information for Homo sapiens
Navigate Across
66643 additional projects are related by organism.
Nuclear FTY720-P is a potent inhibitor of class I histone deacetylases (HDACs) that enhances histone acetylations and regulates expression of a restricted set of genes independently of its known effects on canonical signaling through sphingosine-1-phosphate (S1P) receptors. More...
AccessionPRJNA285668; GEO: GSE69462
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsHait NC et al., "The phosphorylated prodrug FTY720 is a histone deacetylase inhibitor that reactivates ERα expression and enhances hormonal therapy for breast cancer.", Oncogenesis, 2015 Jun 8;4:e156
SubmissionRegistration date: 2-Jun-2015
Pathology, Virginia Commonwealth University
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots334155
Data volume, Processed Mbytes6
Data volume, Supplementary Mbytes48

Supplemental Content

Related information

Recent activity

Clear Turn Off Turn On
  • Ginkgo biloba
    Ginkgo biloba
    Ginkgo biloba Raw sequence reads
    BioProject
  • gut metagenome
    gut metagenome
    jejunum/Colon Targeted Locus (Loci)
    BioProject
  • Homo sapiens
    Homo sapiens
    The phosphorylated prodrug FTY720 is a histone deacetylase Q15 inhibitor that reactivates ERα expression and enhances hormonal therapy for breast cancer
    BioProject
  • Escherichia coli
    Escherichia coli
    Genomic sequencing of Escherichia coli bloodstream isolates
    BioProject
  • Mus musculus
    Mus musculus
    Modeling the time resolved transcriptional signature of time sequential stimulation with HGF and IL-6 in hepatocyte proliferation
    BioProject

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI
Support Center