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Accession: PRJNA285507 ID: 285507

Homo sapiens (human)

Impact of NOD2 Genotype on the Innate Monocyte Transcriptome in Crohn’s Disease

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Short title: Innate Gene/miRNA MDP-response in CD RNA-seq and small RNA-seq were used to identify the expression of gene and microRNA (miRNA) in monocytes from healthy controls and patients with Crohn's Disease (CD), with and without NOD2 (nucleotide-binding oligomerization domain-containing protein 2) single nucleotide polymorphisms (SNPs) after stimulation with muramyl dipeptide (MDP). More...
AccessionPRJNA285507; GEO: GSE69446
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsChen Y et al., "Relation between NOD2 genotype and changes in innate signaling in Crohn's disease on mRNA and miRNA levels.", NPJ Genom Med, 2017;2:3
SubmissionRegistration date: 1-Jun-2015
Health & Nutrition, Chr Hansen A/S
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments28
Publications
PubMed1
PMC1
Other datasets
BioSample28
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes1739
SRA Data Details
ParameterValue
Data volume, Gbases66
Data volume, Mbytes43656

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