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Accession: PRJNA285080 ID: 285080

Mus musculus (house mouse)

Histone H3K36M mutation impairs mesenchymal differentiation and drives sarcoma development [RNA_H33_K36M_HMT]

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This project is a component of the H3K36 mutations promote sarcomagenesis through genome-wide remodeling of H3K36 and H3K27 methylation
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8 additional projects are components of the H3K36 mutations promote sarcomagenesis through genome-wide remodeling of H3K36 and H3K27 methylation.
47588 additional projects are related by organism.
The goal of this study is to understand the alterations in transcriptome induced by histone H3K36M mutations Overall design: Transcritome profiling of 3 cell lines cultured in vitro and 6 murine tumors
AccessionPRJNA285080; GEO: GSE69285
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsLu C et al., "Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape.", Science, 2016 May 13;352(6287):844-9
SubmissionRegistration date: 27-May-2015
Room 2174, Wisconsin Institute for Discovery, Department of Biomolecular Chemistry, University of Wisconsin-Madison
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments18
Publications
PubMed1
PMC1
Other datasets
BioSample18
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes4
SRA Data Details
ParameterValue
Data volume, Gbases68
Data volume, Mbytes42114

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