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1 additional project is a component of the The lncRNA LUST promotes CCICs self-renewal stimulating the wnt/b-catenin signaling activation.
Comprehensive RNA-seq experiments in CD24bright/CD44bright (CCICs), CD24dim/CD44dim (more differentiated counterpart) cells and colonospheres delineate the role of the lncRNA LUST in promoting CCICs self-renewal
Overall design: Identification of lncRNAs binding to Beta-catenin in two different colon cancer cell lines: HT-29 and CaCo-2
| Accession | PRJNA284940; GEO: GSE69234 |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Di Cecilia S et al., "RBM5-AS1 Is Critical for Self-Renewal of Colon Cancer Stem-like Cells.", Cancer Res, 2016 Oct 1;76(19):5615-5627 |
| Grants | - "Chromatin Dynamics of the CFTR locus" (Grant ID R01 HL103967, National Heart, Lung, and Blood Institute)
- "Non-coding RNAs for Epigenetic Transcriptional Silencing in Prostate Cancer" (Grant ID R01 CA154809, National Cancer Institute)
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| Submission | Registration date: 26-May-2015
Structural and Chemical Biology, Mount Sinai School of Medicine |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 4 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 4 |
| GEO DataSets | 1 |