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Accession: PRJNA284684 ID: 284684

Mus musculus (house mouse)

Lysosomal and phagocytic activity is increased in astrocytes during the progression of amyotrophic lateral sclerosis

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47588 additional projects are related by organism.
The aim of the present study is to combine LCM and microarray analysis to study how astrocytes in the spinal cord of transgenic SOD1 G93A mice and their non-transgenic (NTg) littermates respond to stimuli determined by the presence of the human mutant protein throughout the evolution of the disease by looking at the symptomatic and late-stage disease time points. More...
AccessionPRJNA284684; GEO: GSE69166
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsBaker DJ et al., "Lysosomal and phagocytic activity is increased in astrocytes during disease progression in the SOD1 (G93A) mouse model of amyotrophic lateral sclerosis.", Front Cell Neurosci, 2015;9:410
SubmissionRegistration date: 22-May-2015
Heath, Academic Neurology Unit, University of Sheffield
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots541212
Data volume, Processed Mbytes14
Data volume, Supplementary Mbytes39

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