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Accession: PRJNA284675 ID: 284675

Homo sapiens (human)

EpCAM-Aptamer Toxin Conjugates for targeting tumors

See Genome Information for Homo sapiens
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66644 additional projects are related by organism.
Neocarzinostatin (NCS) is an anti-tumor DNA damaging agent. Conjugating NCS with EpCAM Aptamer will direct the toxin pay loads to the EpCAM positive cancer cells as a targeted therapy We used microarrays to detail the global gene expression to understand the pathways involved in EpCAM-mediated NCS drug delivery in breast cancer cells. More...
AccessionPRJNA284675; GEO: GSE69160
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsAthyala PK et al., "Neocarzinostatin, Aptamer Conjugates for Targeting EpCAM-positive Tumor Cells.", Anticancer Res, 2017 Jul;37(7):3615-3629
SubmissionRegistration date: 22-May-2015
Nanobiotechnology, Nanobiotechnology, Vision Research Foundation
RelevanceMedical
Project Data:
Resource NameNumber
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PubMed1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots296370
Data volume, Processed Mbytes8
Data volume, Supplementary Mbytes9

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