BioProject

We performed a genome-wide methylation study in whole-blood DNA from 404 ischemic stroke patient cohort, distributed across 3 ischemic stroke subtypes: Large-artery atherosclerosis (n=132), Small-artery disease (n=141) and Cardio embolic (n=127) . More...

We performed a genome-wide methylation study in whole-blood DNA from 404 ischemic stroke patient cohort, distributed across 3 ischemic stroke subtypes: Large-artery atherosclerosis (n=132), Small-artery disease (n=141) and Cardio embolic (n=127) . Illumina HumanMethylation450 BeadChip array was used to measure DNA methylation in CpG sites. We performed a genome-wide methylation study in whole-blood DNA from 185 ischemic stroke patient cohort. Illumina HumanMethylation450 BeadChip array was used to measure DNA methylation in CpG sites. Overall design: Bisulphite converted DNA from the 404 samples were hybridised to the Illumina HumanMethylation450 BeadChip array Bisulphite converted DNA from the additional 185 samples [replication cohort] were hybridised to the Illumina HumanMethylation450 BeadChip array Please note that, for the replication cohort [GSM3026613-GSM3026797]; The 'Average Beta normalized data' is provided in the betas_normalized_meneas_185.txt & pval_detection_meneas_185.txt Raw 'unmethylated and methylated signal intensities' data is provided in meth_raw_meneas_185.txt & unmeth_raw_meneas_185.txt, and idat files. Less...