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Accession: PRJNA284608 ID: 284608

Homo sapiens (human)

The effect of knockdown Abl kinases on breast cancer cells' global transcriptome

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To gain insight into the signaling pathway(s) required for ABL1/ABL2-dependent bone metastasis, we evaluated the consequences of single or double inactivation of ABL1 and ABL2 on the transcriptome of breast cancer cells. More...
AccessionPRJNA284608; GEO: GSE69125
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsWang J et al., "ABL kinases promote breast cancer osteolytic metastasis by modulating tumor-bone interactions through TAZ and STAT5 signaling.", Sci Signal, 2016 Feb 2;9(413):ra12
SubmissionRegistration date: 21-May-2015
Pendergast lab, Pharmacology and Cancer Biology, Duke University
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments4
Publications
PubMed1
PMC1
Other datasets
BioSample4
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes5
SRA Data Details
ParameterValue
Data volume, Gbases10
Data volume, Mbytes6914

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