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Accession: PRJNA284570 ID: 284570

Induced pluripotent stem cell models of Zellweger spectrum disorder show cell-type-specific lipid abnormalities

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
AccessionPRJNA284570; GEO: GSE69103
TypeUmbrella project
PublicationsWang XM et al., "Induced pluripotent stem cell models of Zellweger spectrum disorder show impaired peroxisome assembly and cell type-specific lipid abnormalities.", Stem Cell Res Ther, 2015 Aug 29;6:158
SubmissionRegistration date: 21-May-2015
Hacia Lab, Biochemistry and Molecular Biology, University of Southern California
RelevanceSuperseries
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets4
GEO Data Details
ParameterValue
Data volume, Spots20755183
Data volume, Processed Mbytes490
Data volume, Supplementary Mbytes276
This project encompasses the following 3 sub-projects:
Project TypeNumber of Projects
Epigenomics1
BioProject
accession
OrganismTitle
PRJNA284400Homo sapiensDNA methylation profiles of fibroblasts and induced pluripotent stem cells (iPSCs) from individuals with Zellweger spectrum disorder (ZSD), a class of peroxisome biogenesis disorder, and healthy controls (Hacia Lab, Biochemistry and...)
Transcriptome or Gene expression2
BioProject
accession
OrganismTitle
PRJNA188315Homo sapiensGene expression profiles of fibroblasts and induced pluripotent stem cells (iPSCs) from individuals with Zellweger spectrum disorder (ZSD), a class of peroxisome biogenesis disorder, and healthy controls (Hacia Lab, Biochemistry and...)
PRJNA284439Homo sapiensGene expression profiles of hepatocyte-like cells derived from induced pluripotent stem cells (iPSCs) from donors with the Zellweger spectrum of peroxisome biogenesis disorders (PBD-ZSD) and healthy controls (Hacia Lab, Biochemistry and...)

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