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Genome Information for Homo sapiens
anti-CD3 + anti-CD46 stimulation for 2hr
Patient has a mutation in CD46 that leads to reduced cell surface CD46 expression and suffers from episodes of atypical hemolytic uremic syndrome (aHUS), common variable immune deficiency (CVID) and recurrent infections
Overall design: total RNA isolated from CD4+ T cells
| Accession | PRJNA284507; GEO: GSE69090 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Arbore G et al., "T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.", Science, 2016 Jun 17;352(6292):aad1210 |
| Submission | Registration date: 20-May-2015
Asthma Allergy & Respiratory Science, King's College London |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 283938 |
| Data volume, Processed Mbytes | 9 |
| Data volume, Supplementary Mbytes | 12 |