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Accession: PRJNA284278 ID: 284278

Mus musculus (house mouse)

Dnmt3l-knockout donor cells improve somatic cell nuclear transfer reprogramming efficiency

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47588 additional projects are related by organism.
We found that Dnmt3l-KO donor cells display decreased levels of H3K9me3 and H3K27me3 accumulation, higher level of active histone mark H3K27ac and increased cytoplasmic localization of HDAC1, implicating a permissive epigenetic state beneficial for nuclear reprogramming. More...
AccessionPRJNA284278; GEO: GSE69007
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsLiao HF et al., "Dnmt3l-knockout donor cells improve somatic cell nuclear transfer reprogramming efficiency.", Reproduction, 2015 Oct;150(4):245-56
SubmissionRegistration date: 18-May-2015
Institute of Biotechnology, National Taiwan University
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments4
Publications
PubMed1
Other datasets
BioSample4
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes6
SRA Data Details
ParameterValue
Data volume, Gbases87
Data volume, Mbytes55177

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