See
Genome Information for Homo sapiens
Cell populations with different invasiveness were isolated and collected with cell culture inserts of Boyden-type cell invasion chambers coated with 1xBME (base membrane extract). Cells that invaded to bottom chamber were collected as cell population with high-invasiveness , and cells that remained in the insert chamber were collected as cell population with low-invasiveness. The selection with Boyden-type cell invasion chambers was repeated six times, and cells with high invasiveness were terms as H-INV subline, and cells with low invasiveness were termed as L-INV subline. Microarray analysis was performed with Illumina HumanHT-12 v4 Expression BeadChips
Overall design: The transcriptional profile of invaded cell subpopulations (H-INV, n=3) was compared to non-invaded cell subpopulations (L-INV, n=3), 968 genes were found to be differentially expressed compared with fold changes more than 2 and FDR <0.05.
| Accession | PRJNA284113; GEO: GSE68916 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Zhang S et al., "Epigenetic therapy potential of suberoylanilide hydroxamic acid on invasive human non-small cell lung cancer cells.", Oncotarget, 2016 Oct 18;7(42):68768-68780 |
| Submission | Registration date: 15-May-2015
Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
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| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 283920 |
| Data volume, Processed Mbytes | 9 |
| Data volume, Supplementary Mbytes | 12 |