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Genome Information for Mus musculus
Gene expression changes in metastasis associated macrophage (MAM) with control and FLT1 inhibitory antibody (MF1) were compared using FACS sorted cells from mice bearing pulmonary metastasis of breast tumor cells treated with Ctrl and MF1 antibody
Overall design: A six chip study using total RNA recovered from metastasis associated macrophages from three separate mice treated with FLT1 inhibitory antibody (MF1) and three separate mice treated with control antibody. Each chip measures the expression level of 42586 genes.
| Accession | PRJNA283865; GEO: GSE68843 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Publications | Qian BZ et al., "FLT1 signaling in metastasis-associated macrophages activates an inflammatory signature that promotes breast cancer metastasis.", J Exp Med, 2015 Aug 24;212(9):1433-48 |
| Submission | Registration date: 13-May-2015 MRC Centre for Reproductive Health, University of Edinburgh |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number of Links |
|---|
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 255516 |
| Data volume, Processed Mbytes | 5 |
| Data volume, Supplementary Mbytes | 46 |