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Accession: PRJNA283865 ID: 283865

Mus musculus (house mouse)

Transcriptom analysis of FLT1 regulated genes in metastasis associated macrophages

See Genome Information for Mus musculus
Gene expression changes in metastasis associated macrophage (MAM) with control and FLT1 inhibitory antibody (MF1) were compared using FACS sorted cells from mice bearing pulmonary metastasis of breast tumor cells treated with Ctrl and MF1 antibody Overall design: A six chip study using total RNA recovered from metastasis associated macrophages from three separate mice treated with FLT1 inhibitory antibody (MF1) and three separate mice treated with control antibody. Each chip measures the expression level of 42586 genes.
AccessionPRJNA283865; GEO: GSE68843
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsQian BZ et al., "FLT1 signaling in metastasis-associated macrophages activates an inflammatory signature that promotes breast cancer metastasis.", J Exp Med, 2015 Aug 24;212(9):1433-48
SubmissionRegistration date: 13-May-2015
MRC Centre for Reproductive Health, University of Edinburgh
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots255516
Data volume, Processed Mbytes5
Data volume, Supplementary Mbytes46

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