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Accession: PRJNA282532 ID: 282532

Homo sapiens (human)

Genome-wide DNA methylation profiles of 20 paired (normal and varicose) vein samples from the patients with varicose vein disease.

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This project is a component of the Profiles of 20 paired (normal and varicose) vein samples from the patients with varicose vein disease
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1 additional project is a component of the Profiles of 20 paired (normal and varicose) vein samples from the patients with varicose vein disease.
66643 additional projects are related by organism.
To identify genes involved in the formation of a pathological phenotype of varicose veins, we attempted to analyze the methylome of their constituent cells and compare it to the methylome of normal veins from the same patient. More...
AccessionPRJNA282532; GEO: GSE68319
Data TypeEpigenomics
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsSmetanina MA et al., "DNA methylation and gene expression profiling reveal MFAP5 as a regulatory driver of extracellular matrix remodeling in varicose vein disease.", Epigenomics, 2018 Aug;10(8):1103-1119
SubmissionRegistration date: 27-Apr-2015
Laboratory of Pharmacogenomics, Institute of Chemical Biology and Fundamental Medicine SB RAS
RelevanceMedical
Project Data:
Resource NameNumber
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Publications
PubMed1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots551560
Data volume, Processed Mbytes16
Data volume, Supplementary Mbytes17

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