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Accession: PRJNA282134 ID: 282134

Homo sapiens (human)

Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.

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This project is a component of the Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.
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1 additional project is a component of the Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer..
66644 additional projects are related by organism.
Mutant p53 proteins, resulting from the missense mutations of the TP53 tumor suppressor gene, possess gain-of-function activities and are among the most robust oncoproteins in human tumors. More...
AccessionPRJNA282134; GEO: GSE68248
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsWalerych D et al., "Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.", Nat Cell Biol, 2016 Aug;18(8):897-909
SubmissionRegistration date: 24-Apr-2015
CIBIO, University of Trento
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments6
Publications
PubMed1
Other datasets
BioSample6
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes5
SRA Data Details
ParameterValue
Data volume, Gbases38
Data volume, Mbytes25304

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