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Accession: PRJNA282078 ID: 282078

Homo sapiens (human)

Alternative splicing in genes encoding adhesion- and motility-related proteins in breast cancer

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66644 additional projects are related by organism.
In this study, combining 1) RNA-Sequencing on MCF-7 cell line, 2) a new computational approach to identify splice isoforms and 3) an extensive experimental validation (in vitro - on MCF-10, MCF-7 and MDA-MB-231 – and ex vivo – on human breast cancer tissues) we investigated simultaneously gene expression and alternative splicing in genes encoding for adhesion and motility-related molecules-, including Semaphorins and their receptors and co-receptors. More...
AccessionPRJNA282078; GEO: GSE68228
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsAversa R et al., "Alternative Splicing in Adhesion- and Motility-Related Genes in Breast Cancer.", Int J Mol Sci, 2016 Jan 16;17(1)
SubmissionRegistration date: 24-Apr-2015
Institute of Genetics and Biophysics, National Research Council
RelevanceMedical
Project Data:
Resource NameNumber
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Sequence data
SRA Experiments2
Publications
PubMed1
PMC1
Other datasets
BioSample2
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes2
SRA Data Details
ParameterValue
Data volume, Gbases10
Data volume, Mbytes7413

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