See
Genome Information for Homo sapiens
SOX7 was commonly downregulated in AML by hypermethylation.
Re-expression of SOX7 in AML reduced the survival of AML
Overall design: Overexpression of GFP-SOX7 by lenti-viral transduction in 3 AML cell lines and compared the expression level of genes normalized to GFP control
| Accession | PRJNA280988; GEO: GSE67817 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Man CH et al., "Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia.", Blood, 2015 Jun 18;125(25):3928-36 |
| Submission | Registration date: 13-Apr-2015
HKU |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 199782 |
| Data volume, Processed Mbytes | 4 |
| Data volume, Supplementary Mbytes | 31 |