To explore the changes of proportion and diversity of gut microbiota before and after treatment with acarbose in pre-diabetes, we designed a randomized, double-blind and controlled crossover trial in which 52 pre-diabetes aged 30-60 years with BMI 18-35 kg/m2 by OGTT in China were randomly allocated to treatment with acarbose or placebo for 3 months.
More...To explore the changes of proportion and diversity of gut microbiota before and after treatment with acarbose in pre-diabetes, we designed a randomized, double-blind and controlled crossover trial in which 52 pre-diabetes aged 30-60 years with BMI 18-35 kg/m2 by OGTT in China were randomly allocated to treatment with acarbose or placebo for 3 months. Gut microbiota characterizations were determined with 16S rDNA-based high-throughput sequencing. The alpha diversity was estimated by Shannon index, chao1 index and the beta diversity was estimated by PCA analysis
Less...| Accession | PRJEB8450 |
| Scope | Monoisolate |
| Submission | Registration date: 11-Apr-2015
Jianghan University |
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