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Accession: PRJNA280755 ID: 280755

Mus musculus (house mouse)

Network analysis of gene expression in mice provides new evidence of involvement of the mTOR pathway in antipsychotic-induced extrapyramidal symptoms

See Genome Information for Mus musculus
To identify potential candidate genes for future pharmacogenetic studies of antipsychotic (AP)-induced extrapyramidal symptoms (EPS), we used gene expression arrays to analyze changes induced by risperidone in mice strains with different susceptibility to EPS This study is a part of a convergent functional genomic approach that plans to integrate the data presented here with: data from gene expression analysis of neuroblastoma cell line under treatment with risperidone; and data from gene expression analysis of peripheral blood from first psychotic patients treated with risperidone. More...
AccessionPRJNA280755; GEO: GSE67723
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsMas S et al., "Network analysis of gene expression in mice provides new evidence of involvement of the mTOR pathway in antipsychotic-induced extrapyramidal symptoms.", Pharmacogenomics J, 2016 Jun;16(3):293-300
SubmissionRegistration date: 9-Apr-2015
Pharmacology, School of Medicine, University of Barcelona
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots722256
Data volume, Processed Mbytes14
Data volume, Supplementary Mbytes35

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