See
Genome Information for Homo sapiens
Identification of genes and pathways altered by PlaB, a bacterial natural product that acts as a spliceosome modulator by targeting the SF3b subunit of the spliceosome
Overall design: SKNMC, TC32, TC71, and RD-ES Ewing sarcoma cell lines were treated with 0.1% (v/v) DMSO vehicle or 5nM PlaB for 24 hours. Three samples in each group were analyzed.
| Accession | PRJNA280223; GEO: GSE67548 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Grohar PJ et al., "Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma.", Cell Rep, 2016 Jan 26;14(3):598-610 |
| Submission | Registration date: 2-Apr-2015
Gene Silencing Section, Genetics Branch, CCR, NCI, NIH |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 1135704 |
| Data volume, Processed Mbytes | 20 |
| Data volume, Supplementary Mbytes | 46 |