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Accession: PRJNA280212 ID: 280212

Homo sapiens (human)

MicroRNA profile in Castleman disease

See Genome Information for Homo sapiens
To elucidate the aetiology of Castleman disease, especially with regard to microRNA (miRNA) profiles, samples obtained from three different parts of both normal and tumour tissues were analysed. The details of RNA extraction have been described in our previous reports. Interestingly, 3 miRNAs were significantly up-regulated and 31 miRNAs were down-regulated in the tumour tissues compared to the normal tissues (Student’s t-test, p<0.01). In addition, unsupervised hierarchical clustering analysis using a Pearson’s correlation showed that the tumour tissues clustered separately from the normal tissues. Overall design: microRNA samples obtained from three different parts of both normal and tumour tissues were analysed.
AccessionPRJNA280212; GEO: GSE67538
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
SubmissionRegistration date: 2-Apr-2015
New Projects Development Division, Toray Industries,Inc.
RelevanceMedical
Project Data:
Resource NameNumber
of Links
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots15330
Data volume, Processed Mbytes1
Data volume, Supplementary Mbytes1

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