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Accession: PRJNA280091 ID: 280091

Homo sapiens (human)

Reverse phase protein arrays (RPPAs): effects of MPS1 inhibition on signaling pathways in GBM cells

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To determine the biological effects of MPS1 inhibition (both by siRNA and Drug (NMSP715)) on signaling pathways in GBM cells (U251 &U87), we profiled the modulation of phosphorylated and non-phosphorylated proteins using RPPA Overall design: Relative protein levels for each sample were determined by interpolation of each dilution curves from the standard curve antibody slide. More...
AccessionPRJNA280091; GEO: GSE67502
Data TypeProteome
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsMaachani UB et al., "Modulation of miR-21 signaling by MPS1 in human glioblastoma.", Oncotarget, 2016 Aug 16;7(33):52912-52927
SubmissionRegistration date: 1-Apr-2015
Radiation Oncology Branch, NCI, NIH
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots4128
Data volume, Processed Mbytes1
Data volume, Supplementary Mbytes1

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