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Accession: PRJNA279682 ID: 279682

Mus musculus (house mouse)

Effect of aryl hydrocarbon receptor (Ahr) gene knockout on expression profiles of aged (18-month-old) murine hematopoietic stem cells

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As part of a study of the role of the aryl hydrocarbon receptor (Ahr) in maintenance and senescence of hematopoietic stem cells (HSC), global gene expression profiling was done with HSC isolated from 18-month-old Ahr-knockout and wild-type mice. More...
AccessionPRJNA279682; GEO: GSE67378
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications
  • Bennett JA et al., "Conditional deletion of Ahr alters gene expression profiles in hematopoietic stem cells.", PLoS One, 2018;13(11):e0206407
  • Bennett JA et al., "Deficiency in Aryl Hydrocarbon Receptor (AHR) Expression throughout Aging Alters Gene Expression Profiles in Murine Long-Term Hematopoietic Stem Cells.", PLoS One, 2015;10(7):e0133791
SubmissionRegistration date: 27-Mar-2015
University of Rochester
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Publications
PubMed2
PMC2
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots413450
Data volume, Processed Mbytes9
Data volume, Supplementary Mbytes81

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