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Accession: PRJNA279530 ID: 279530

Mus musculus (house mouse)

Impact of Lef1 overexpression on follicular helper T (Tfh) differentiation

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This project is a component of the LEF-1 and TCF-1 orchestrate T follicular helper (Tfh) cell differentiation by regulating Tfh differentiation circuits upstream of Bcl6
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1 additional project is a component of the LEF-1 and TCF-1 orchestrate T follicular helper (Tfh) cell differentiation by regulating Tfh differentiation circuits upstream of Bcl6.
47588 additional projects are related by organism.
Comparison of transcriptome between GFP-RV+ Th1 cells and Lef1-RV+ Th1 cells Overall design: B6 mice received GFP-RV+ or Lef1-RV+ LCMV gp specific TCRtg Smarta cells and were infected with LCMV. More...
AccessionPRJNA279530; GEO: GSE67335
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsChoi YS et al., "LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6.", Nat Immunol, 2015 Sep;16(9):980-90
SubmissionRegistration date: 26-Mar-2015
La Jolla Institute for Allergy and Immunology
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments4
Publications
PubMed1
PMC1
Other datasets
BioSample4
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes1
SRA Data Details
ParameterValue
Data volume, Gbases4
Data volume, Mbytes2463

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