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Accession: PRJNA279167 ID: 279167

Mus musculus (house mouse)

A genome-wide CRISPR screen in primary immune cells to dissect regulatory networks

See Genome Information for Mus musculus
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47588 additional projects are related by organism.
We introduced genome-wide pooled CRISPR-Cas9 libraries into primary mouse dendritic cells (DCs) to identify genes that control the induction of tumor necrosis factor (TNF) by bacterial lipopolysaccharide (LPS), a key process in the host response to pathogens, mediated by the TLR4 pathway. More...
AccessionPRJNA279167; GEO: GSE67164
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsParnas O et al., "A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks.", Cell, 2015 Jul 30;162(3):675-86
SubmissionRegistration date: 23-Mar-2015
Aviv Regev, Biology, BROAD INSTITUTE
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments632
Publications
PubMed1
PMC1
Other datasets
BioSample632
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes21
SRA Data Details
ParameterValue
Data volume, Gbases101
Data volume, Mbytes74309

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