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Accession: PRJNA174416 ID: 174416

Homo sapiens (human)

Genome-Wide STAT5 binding sites in Kit225 leukemia cells

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This project is a component of the Genome-wide mapping of IL-2 regulated target genes and IL-2 activated STAT5 binding sites in Kit225 human leukemia cells.
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1 additional project is a component of the Genome-wide mapping of IL-2 regulated target genes and IL-2 activated STAT5 binding sites in Kit225 human leukemia cells..
66644 additional projects are related by organism.
In order to systematically map STAT5 genomic binding sites and IL-2 mediated gene expression changes we mapped STAT5 binding sites using chip-on-ChIP in IL-2 dependent Kit225 cells that were either left un-stimulated or stimulated with IL-2 for 30 minutes. More...
AccessionPRJNA174416; GEO: GSE40619
Data TypeEpigenomics
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsNagy ZS et al., "Genome wide mapping reveals PDE4B as an IL-2 induced STAT5 target gene in activated human PBMCs and lymphoid cancer cells.", PLoS One, 2013;8(2):e57326
SubmissionRegistration date: 5-Sep-2012
Biochemistry and Molecular Biology, University of Debrecen
RelevanceMedical
Project Data:
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PubMed1
PMC1
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GEO DataSets1
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Data volume, Supplementary Mbytes305

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