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Accession: PRJNA174350 ID: 174350

Homo sapiens (human)

RNAseq analysis of the human neutrophil transcriptome, with and without in vitro cytokine stimulation

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We report cytokine specific changes in gene expression in the human neutrophil transcriptome using TNF-alpha and GM-CSF stimulation of healthy neutrophils Overall design: Healthy human neutrophils were stimulated with TNF-alpha or GM-CSF for 1h in vitro. More...
AccessionPRJNA174350; GEO: GSE40548
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications
  • Chiewchengchol D et al., "Differential changes in gene expression in human neutrophils following TNF-α stimulation: Up-regulation of anti-apoptotic proteins and down-regulation of proteins involved in death receptor signaling.", Immun Inflamm Dis, 2016 Mar;4(1):35-44
  • Wright HL et al., "RNA-seq reveals activation of both common and cytokine-specific pathways following neutrophil priming.", PLoS One, 2013;8(3):e58598
SubmissionRegistration date: 31-Aug-2012
Institute of Ageing and Chronic Disease, University of Liverpool
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments9
Publications
PubMed2
PMC2
Other datasets
BioSample9
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes4
SRA Data Details
ParameterValue
Data volume, Gbases30
Data volume, Mbytes22743

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