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Accession: PRJNA173821 ID: 173821

Homo sapiens (human)

siRNA Knockdown of SWI/SNF complex proteins in prostate cancer cell lines

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This project is a component of the SChLAP-1, a long non-coding RNA, antagonizes the SWI/SNF complex and coordinates aggressive prostate cancer.
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2 additional projects are components of the SChLAP-1, a long non-coding RNA, antagonizes the SWI/SNF complex and coordinates aggressive prostate cancer..
66644 additional projects are related by organism.
Here we performed transcriptional profiling of the prostate cancer cell lines LNCaP and 22Rv1 comparing non-targeting siRNA treatment versus siRNAs targeting SWI/SNF complex proteins (SMARCA2, SMARCA4, and SMARCB1). More...
AccessionPRJNA173821; GEO: GSE40384
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsPrensner JR et al., "The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex.", Nat Genet, 2013 Nov;45(11):1392-8
SubmissionRegistration date: 27-Aug-2012
Chinnaiyan Lab, Michigan Center for Translational Pathology, University of Michigan
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots522348
Data volume, Processed Mbytes16
Data volume, Supplementary Mbytes172

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