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Accession: PRJNA173689 ID: 173689

Mus musculus (house mouse)

A mouse model of rhabdomyosarcoma originating from the adipocyte lineage

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47588 additional projects are related by organism.
Activation of Sonic Hedgehog signaling through expression of a constitutively active Smoothened allele under control of an aP2 adipocyte-restricted transgene in mice gives rise to aggressive skeletal muscle tumors that display the histologic and molecular characteristics of human embryonal rhabdomyosarcoma with high penetrance. More...
AccessionPRJNA173689; GEO: GSE40359
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsHatley ME et al., "A mouse model of rhabdomyosarcoma originating from the adipocyte lineage.", Cancer Cell, 2012 Oct 16;22(4):536-46
SubmissionRegistration date: 24-Aug-2012
Computational Biology, St Jude Children's Research Hospital
RelevanceModel Organism
Project Data:
Resource NameNumber
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Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots950901
Data volume, Processed Mbytes26
Data volume, Supplementary Mbytes6

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