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Accession: PRJNA173382 ID: 173382

A multiply redundant genetic switch locks in the transcriptional signature of T regulatory cells

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
AccessionPRJNA173382; GEO: GSE40278
TypeUmbrella project
PublicationsFu W et al., "A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells.", Nat Immunol, 2012 Oct;13(10):972-80
SubmissionRegistration date: 21-Aug-2012
CBDM, Microbiology and Immunobiology, Harvard Medical School
RelevanceSuperseries
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments4
Publications
PubMed1
PMC1
Other datasets
BioSample4
GEO DataSets6
GEO Data Details
ParameterValue
Data volume, Spots1495320
Data volume, Processed Mbytes26
Data volume, Supplementary Mbytes1631
SRA Data Details
ParameterValue
Data volume, Gbases5
Data volume, Mbytes2813
This project encompasses the following 5 sub-projects:
Project TypeNumber of Projects
Epigenomics1
BioProject
accession
OrganismTitle
PRJNA173245Mus musculusGenome-wide maps of FoxP3 binding in transduced CD4+ T cells (CBDM, Microbiology and Immunobiology,...)
Transcriptome or Gene expression4
BioProject
accession
OrganismTitle
PRJNA173383Mus musculusGene profiling data of CD4+ T cells transduced with FOXP3 and GATA1, then sorted into different fractions, based on the expression of Thy1.1 (FOXP3) (CBDM, Microbiology and Immunobiology,...)
PRJNA173384Mus musculusGene profiling data of CD4+ T cells doubly transduced with EOS+LEF1 or GATA1+SATB1 (CBDM, Microbiology and Immunobiology,...)
PRJNA173378Mus musculusGene expression profiling in Treg cells deficient or mutant in candidate FoxP3 cofactors (CBDM, Microbiology and Immunobiology,...)
PRJNA173380Mus musculusGene profiling data of CD4+ T cells transduced with FOXP3 and candidate cofactors (CBDM, Microbiology and Immunobiology,...)

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