See
Genome Information for Homo sapiens
We evaluated the presence of genome-wide epigenetic differences at 385,000 loci using Encode HG18 DNA methylation arrays in 5 non-tumor-associated (NTA) and 4 histologically undistinguished tumor-associated (TA) prostate tissues.
We identified 615 probes to be differentially methylated (p<0.05) in TA prostate, with 537 (87%) hypomethylated and 78 (13%) hypermethylated.
Overall design: comparison of methylation in NTA to TA prostate tissue
| Accession | PRJNA169534; GEO: GSE38982 |
| Data Type | Epigenomics |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Yang B et al., "Methylation profiling defines an extensive field defect in histologically normal prostate tissues associated with prostate cancer.", Neoplasia, 2013 Apr;15(4):399-408 |
| Submission | Registration date: 28-Jun-2012
Urology, UW-Madison |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
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| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 4608168 |
| Data volume, Processed Mbytes | 54 |
| Data volume, Supplementary Mbytes | 142 |