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Accession: PRJNA167308 ID: 167308

Mus musculus (house mouse)

Expression Profiles of PMH treated with 7µM of the genotoxic compound cisplatin

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This project is a component of the Characterization of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows a strong conservation of involved transcription factors
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1 additional project is a component of the Characterization of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows a strong conservation of involved transcription factors.
47588 additional projects are related by organism.
The transcriptomic changes induced in primary mouse hepatocytes (C57BL/6 ) by 7µM of cisplatin after treatment for 24 and 48h Overall design: The study investigated differential gene expression in PMH mRNA following 24 and 48 hours of exposure to 7µM of cisplatin and its solvent. Three biological replicates per compound/solvent. In total 12 arrays.
AccessionPRJNA167308; GEO: GSE38123
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsRieswijk L et al., "Characterisation of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows conservation of regulating transcription factor networks.", Mutagenesis, 2014 Jan;29(1):17-26
SubmissionRegistration date: 22-May-2012
Toxicogenomics, Maastricht University
RelevanceModel Organism
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PubMed1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots195972
Data volume, Processed Mbytes4
Data volume, Supplementary Mbytes44

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