See
Genome Information for Homo sapiens
Navigate Up
Navigate Across
1 additional project is a component of the Characterization of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows a strong conservation of involved transcription factors.
The transcriptomic changes induced in the human liver cell line HepG2 by 7µM of cisplatin after treatment for 12, 24 and 48h
Overall design: The study investigated differential gene expression in HepG2 cell line mRNA following 12,24 and 48 hours of exposure to 7µM of cisplatin and its solvent. Three biological replicates per compound/solvent. In total 18 arrays .
| Accession | PRJNA167307; GEO: GSE38122 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Rieswijk L et al., "Characterisation of cisplatin-induced transcriptomics responses in primary mouse hepatocytes, HepG2 cells and mouse embryonic stem cells shows conservation of regulating transcription factor networks.", Mutagenesis, 2014 Jan;29(1):17-26 |
| Submission | Registration date: 22-May-2012
Toxicogenomics, Maastricht University |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 319068 |
| Data volume, Processed Mbytes | 7 |
| Data volume, Supplementary Mbytes | 86 |