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Genome Information for Mus musculus
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This program aims at identifying the lung gene signature associated with inflammation and emphysema in IL-1b-Tg mouse COPD model to facilitate understanding of the disease mechanism and therapeutic compound testing
Overall design: The lung profiling data was analyzed by identifying genes that were up- and down-regulated at selected p value and fold change in the lungs of IL-1b-Tg mice treated with doxycycline (to induce IL-1b transgene) compared to the corresponding water-treated controls.
| Accession | PRJNA167188; GEO: GSE38075 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Publications | Wang IM et al., "Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers.", Mol Syst Biol, 2012 Jul 17;8:594 |
| Submission | Registration date: 21-May-2012
Research Solutions and Bioinformatics, Informatics and Analysis, Merck Research Lab |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 349448 |
| Data volume, Processed Mbytes | 9 |
| Data volume, Supplementary Mbytes | 29 |