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Accession: PRJNA159419 ID: 159419

Plasmodium falciparum (malaria parasite P. falciparum)

CGH of Plasmodium falciparum selected with DSM1

See Genome Information for Plasmodium falciparum
Continual challenge of 107 ARMD Dd2 parasites with 0.3µM DSM1, a novel dihydroorotate dehydrogenase (DHODH) inhibitor, reproducibly generated ~5-fold resistance and 3-fold amplification of 30-100Kb DNA, always including the DHODH gene. More...
AccessionPRJNA159419; GEO: GSE37306
Data TypeVariation
ScopeMultiisolate
OrganismPlasmodium falciparum[Taxonomy ID: 5833]
Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum
PublicationsGuler JL et al., "Asexual populations of the human malaria parasite, Plasmodium falciparum, use a two-step genomic strategy to acquire accurate, beneficial DNA amplifications.", PLoS Pathog, 2013;9(5):e1003375
SubmissionRegistration date: 16-Apr-2012
Rathod, Chemistry, University of Washington
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots3084680
Data volume, Processed Mbytes77
Data volume, Supplementary Mbytes93

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