Single embryo transfer (SET) is the most successful way to reduce the frequency of multiple pregnancies during in vitro fertilisation. However, selecting the embryo with the highest chances of pregnancy for SET remains a difficult challenge, since morphological and kinetics criteria provide poor prediction of both developmental and implantation ability. Partly through the expression of specific genes, the oocyte-cumulus interaction helps the oocyte to acquire its developmental competence. Our aim was therefore to identify at the level of cumulus cells (CCs) any genes related to oocyte developmental competence.
This SuperSeries is composed of the SubSeries listed below.
Overall design: Refer to individual Series.
| Accession | PRJNA159251; GEO: GSE37277 |
| Type | Umbrella project |
| Publications | Feuerstein P et al., "Genomic assessment of human cumulus cell marker genes as predictors of oocyte developmental competence: impact of various experimental factors.", PLoS One, 2012;7(7):e40449 |
| Submission | Registration date: 15-Apr-2012
INSERM U915 |
| Relevance | Superseries |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 4 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 4141380 |
| Data volume, Processed Mbytes | 72 |
| Data volume, Supplementary Mbytes | 656 |
This project encompasses the following 3 sub-projects:
| Project Type | Number of Projects |
| Transcriptome or Gene expression | 3 |
BioProject
accession | Organism | Title |
|---|
| PRJNA158269 | Homo sapiens | Differentiating factors of cumulus cells related to quality of the human oocyte [CadoretPart1] (INSERM U915) | | PRJNA159445 | Homo sapiens | Differentiating factors of cumulus cells related to quality of the human oocyte [CadoretPart3] (INSERM U915) | | PRJNA159447 | Homo sapiens | Differentiating factors of cumulus cells related to quality of the human oocyte [CadoretPart2] (INSERM U915) |
|