See
Genome Information for Rattus norvegicus
The aim of this study is the characterize and compare heart and PBMC transcriptomes of rats treated with doxorubicin in order to isolate a list of similarly differentially regulated genes with an ultimate goal to indentify PBMC biomarkers for early prediction of doxirubicinduced cardiotoxicity
Overall design: Total RNA was isolated from PBMC and hearts of rats treated with doxirubicin or saline for 48 hrs and used for gene expression
| Accession | PRJNA159147; GEO: GSE37260 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Rattus norvegicus[Taxonomy ID: 10116] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus |
| Publications | Todorova VK et al., "Transcriptome profiling of peripheral blood cells identifies potential biomarkers for doxorubicin cardiotoxicity in a rat model.", PLoS One, 2012;7(11):e48398 |
| Submission | Registration date: 13-Apr-2012
UAMS |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
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| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 765782 |
| Data volume, Processed Mbytes | 19 |
| Data volume, Supplementary Mbytes | 3 |