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Accession: PRJNA156717 ID: 156717

Homo sapiens (human)

Transcriptome profiling of trisomy 21 and euploid iPSC-derived hematopoietic progenitors expressing wtGATA1 or an amino-truncated isoform of GATA1, GATA1short (GATA1s).

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This project is a component of the Pluripotent stem cells reveal novel erythroid activities of the GATA1 N-terminus
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2 additional projects are components of the Pluripotent stem cells reveal novel erythroid activities of the GATA1 N-terminus.
66644 additional projects are related by organism.
We generated human induced pluripotent stem cells (iPSCs) from trisomy 21 (T21) and euploid patient tissues with and without GATA1 mutations causing exclusive expression of truncated GATA1, termed GATA1short (GATA1s). More...
AccessionPRJNA156717; GEO: GSE36787
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsByrska-Bishop M et al., "Pluripotent stem cells reveal erythroid-specific activities of the GATA1 N-terminus.", J Clin Invest, 2015 Mar 2;125(3):993-1005
SubmissionRegistration date: 25-Mar-2012
Pennsylvania State University
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots432861
Data volume, Processed Mbytes9
Data volume, Supplementary Mbytes49

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