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Accession: PRJNA156287 ID: 156287

Homo sapiens (human)

Impact of miR-199-5p overexpression and CAV1 silencing on human lung fibroblasts

See Genome Information for Homo sapiens
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This project is a component of the MiR-199a-5p determines fibroblast activation and pulmonary fibrogenesis
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2 additional projects are components of the MiR-199a-5p determines fibroblast activation and pulmonary fibrogenesis.
66644 additional projects are related by organism.
To identify putative novel specific targets of mir-199-5p, we overexpressed miR-199a-5p as well as miR-21 and a siRNA targeted against CAV1 in human HFL1 pulmonary fibroblasts (CCL-153) by transfecting them with synthetic pre-miRNAs or a synthetic “negative” pre-miRNA as control (miR-Neg). More...
AccessionPRJNA156287; GEO: GSE34815
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsLino Cardenas CL et al., "miR-199a-5p Is upregulated during fibrogenic response to tissue injury and mediates TGFbeta-induced lung fibroblast activation by targeting caveolin-1.", PLoS Genet, 2013;9(2):e1003291
SubmissionRegistration date: 3-Jan-2012
Functional Genomics Platform of Nice-Sophia-Antipolis, France., IPMC/CNRS
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots881664
Data volume, Processed Mbytes15
Data volume, Supplementary Mbytes171

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