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1 additional project is a component of the GATA-1 in proliferating and differentiating murine ES cell derived erythroid progenitors.
We find GATA-1 occupies 6,600 sites in proliferating erythroid progenitors and 10,600 sites in differentiating progenitors. 80-90% of GATA-1 binds within intragenic or intergenic regions, while <20% of GATA-1 is found within 2kb of TSS.
Overall design: Assaying GATA-1 occupancy in normal erythroid progenitors in both proliferating and differentiating conditions.
| Accession | PRJNA156065; GEO: GSE35379 |
| Data Type | Epigenomics |
| Scope | Multiisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Publications | Wontakal SN et al., "A core erythroid transcriptional network is repressed by a master regulator of myelo-lymphoid differentiation.", Proc Natl Acad Sci U S A, 2012 Mar 6;109(10):3832-7 |
| Submission | Registration date: 27-Jan-2012
Dr. Art Skoultchi, Cell Biology, Albert Einstein College of Medicine |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
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| Sequence data |
| SRA Experiments | 6 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 6 |
| GEO DataSets | 1 |