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1 additional project is a component of the Integrative array-based approach identifies MZB1 as a frequently methylated putative tumor-suppressor in hepatocellular carcinoma.
The analysis of DNA methylation profiles was performed by methylated DNA immunoprecipitation (MeDIP) using anti-5-methylcytidine antibody (Eurogentec, Seraing, Belgium) followed by the Human 244K Agilent CpG island microarray (Agilent, Santa Clara, CA)
Overall design: Genomic DNAs from Hep3B, HepG2 and HuH-7 cells were used for cancer samples and that from a normal liver tissue from surgical sample of colon cancer metastasis, as a control sample (C20)
| Accession | PRJNA156019; GEO: GSE35312 |
| Data Type | Epigenomics |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Matsumura S et al., "Integrative array-based approach identifies MZB1 as a frequently methylated putative tumor suppressor in hepatocellular carcinoma.", Clin Cancer Res, 2012 Jul 1;18(13):3541-51 |
| Submission | Registration date: 31-Mar-2012
Prof. Inazawa's Lab, Dept. of Mol. Cytogenet., Inst. of Med. Sci., Tokyo Med. & Dent. Univ. |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
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| Publications |
| PubMed | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 974016 |
| Data volume, Processed Mbytes | 23 |
| Data volume, Supplementary Mbytes | 96 |