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4 additional projects are components of the Systematic Discovery of Structural Elements Governing Mammalian mRNA Stability.
Transcriptional profiling of MDA-MB-231 samples taken at 0, 1, 2 and 4hr timepoints upon exposure to alpha-amanitine, comparing the siRNA-mediated HNRPA2B1 knock-downs versus mock-transfected controls
Overall design: 4 biological replicates for each time point for the siRNA transfections and controls respectively
| Accession | PRJNA155927; GEO: GSE35756 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Goodarzi H et al., "Systematic discovery of structural elements governing stability of mammalian messenger RNAs.", Nature, 2012 Apr 8;485(7397):264-8 |
| Submission | Registration date: 13-Feb-2012
Columbia University |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 1440480 |
| Data volume, Processed Mbytes | 28 |
| Data volume, Supplementary Mbytes | 289 |