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1 additional project is a component of the PABPN1 role in regulation of alternative cleavage and polyadenylation.
We applied deep-sequencing based technique, 3'-Seq, to obtain comprehansive maps of poly-A sites in OPMD-model mice expressing trePABPN1(A17) mutant and control mice
Overall design: Examination of poly-A sites in control and OPMD-model mice (in two ages: 20 weeks and 12 months)
| Accession | PRJNA154499; GEO: GSE32302 |
| Scope | Multiisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Publications | Jenal M et al., "The poly(A)-binding protein nuclear 1 suppresses alternative cleavage and polyadenylation sites.", Cell, 2012 Apr 27;149(3):538-53 |
| Submission | Registration date: 22-Sep-2011
Human Genetics, Tel Aviv University |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
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| Sequence data |
| SRA Experiments | 10 |
| Publications |
| PubMed | 1 |
| Other datasets |
| BioSample | 10 |
| GEO DataSets | 1 |