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Accession: PRJNA154321 ID: 154321

Homo sapiens (human)

Distinct effects of topoisomerase II inhibitors on tumor cell lines (part 1)

See Genome Information for Homo sapiens
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This project is a component of the Topoisomerase II inhibitors and histone eviction
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4 additional projects are components of the Topoisomerase II inhibitors and histone eviction.
66644 additional projects are related by organism.
One major class of anti-cancer drugs targets topoisomerase II to induce DNA double-strand breaks and cell death of fast growing cells. More...
AccessionPRJNA154321; GEO: GSE33624
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsPang B et al., "Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin.", Nat Commun, 2013;4:1908
SubmissionRegistration date: 11-Nov-2011
Jacques Neefjes, Cell Bioloy II, The Netherlands Cancer Institute
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots681814
Data volume, Processed Mbytes22
Data volume, Supplementary Mbytes10

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