In a large-scale comparative genomics analysis of hemiascomycetes yeasts, the
Genolevures Consortium partially sequenced the genomes of 13 yeasts, including that of
Candida tropicalis strain CBS 94.
More...In a large-scale comparative genomics analysis of hemiascomycetes yeasts, the
Genolevures Consortium partially sequenced the genomes of 13 yeasts, including that of
Candida tropicalis strain CBS 94. For each species, they prepared a random genomic DNA library containing 3- to 5-kb inserts and performed single-pass sequencing (up to 1 kb) of both ends of the inserts, resulting in random sequence tags (RSTs). The
Genolevures Consortium generated 2,541 RSTs, totaling 2.3 Mb and representing approximately 0.2X genome coverage, for
Candida tropicalis. They assembled these sequences into contigs and annotated them based on sequential comparisons to DNA and protein sequences from
Saccharomyces cerevisiae, protein sequences from other completely sequenced organisms, and protein sequences from all other organisms. The
Candida tropicalis sequences are available in GenBank/EMBL/DDBJ under the accessions
AL438875 to AL441602.
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