BioProject

Enterococcus faecalis is a species of bacteria that is naturally found in the intestines. More...

Enterococcus faecalis is a species of bacteria that is naturally found in the intestines. While it tends to be harmless in that environment, it has the potential to cause a serious infection if it spreads to other areas of the body. Enterococci are a type of bacteria that live in gastrointestinal (GI) tract. Ampicillin is the drug of choice for monotherapy of susceptible E faecalis infection. For most isolates, the MIC of ampicillin is 2- to 4-fold lower than that of penicillin. For rare strains that are resistant to ampicillin because of beta-lactamase production, ampicillin plus sulbactam may be used. Enterococci are gram-positive, facultative anaerobic organisms. Enterococcus faecalis and E. faecium cause a variety of infections, including endocarditis, urinary tract infections, prostatitis, intra-abdominal infection, cellulitis, and wound infection as well as concurrent bacteremia. If these infections become systemic, they can cause serious to life-threatening symptoms. The isolation and whole genome sequencing of Enterococcus faecalis from environment, human and animal clinical samples could reveal the AMR pattern of the community isolates. Less...