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Comment

CONSTRUCTION: This sequence was assembled from data for the B95-8 (V01555) and Raji (M35547) strains with corrections. The number of IR1 (W) repeats in V01555 has been reduced from 11.6 to a more typical 7.6, and the missing B95-8 ... sequence has been restored to give a sequence more representative of wild type EBV.
NUMBERING: Like the modified B95-8 sequence in V01555, this sequence starts 1 bp to the left of the EcoRI site separating EcoRI Dhet from EcoRI I (i.e. the first A of AGAATTC).
TRANSCRIPTION: Long-range splicing of the EBNA and BART genes generates multiple, complex mRNAs. A single mRNA structure is shown for each gene, but alternatives may initiate at other promoters and may involve various exon combinations. TATA and polyA signals are shown as non-experimental where predicted or as experimental where supporting data are available. Predictions of TATA or polyA signals are not made for some genes.
NOMENCLATURE: The original gene nomenclature has been retained. Genes presumably inherited from the common ancestor of alpha-, beta- and gammaherpesviruses (core genes), from the common ancestor of beta- and gammaherpesviruses (betagamma genes), or from the common ancestor of gammaherpesviruses (gamma genes) are indicated. A standard protein nomenclature has been applied so that orthologs have the same name in all herpesviruses.
CONFIDENCE: Evidence for encoded protein functions is more convincing for some ORFs than others, and rests on a combination of factors, including evolutionary conservation, expression and functional data. The most questionable ORFs are annotated as such.  more

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